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Immuno-Grade Melanin-Concentrating Hormone Receptor 1 (MCH1) Antibodies

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Immunohistochemical identification of Melanin-Concentrating Hormone Receptor 1 in pancreas
MCH1 (IHC-grade) Melanin-Concentrating Hormone...
The non-phospho MCH1 receptor antibody is directed against the distal end of the carboxyl-terminal tail human MCH1 receptor. It can be used to detect total MCH1 receptors in Western blots independent of phosphorylation. It can also be...
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Rabbit Monoclonal
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Immunohistochemical identification of Melanin-Concentrating Hormone Receptor 1 in neuronal cilia
MCH1 [UMB20]...
The non-phospho-MCH1 antibody is directed against the distal end of the carboxyl-terminal tail of human MCH1. It can be used to detect total MCH1 receptors in Western blots independent of phosphorylation. The MCH1 antibody can also be...
$ 495.00 *
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The melanin-concentrating hormone receptor 1 (MCH1) is the receptor for a 19 amino-acids cyclic peptide. The highest expression of MCH1 is found in the brain: frontal cortex, amygdala and nucleus accumbens, but also in the arcuate nucleus and in the ventral medial hypothalamus. MCH1 seems to play a role in appetite regulation and obesity. Knock out mice for MCH1 are leaner, even on high fat diet. Several antagonists at MCH1 showed antidepressant and anxiolytic activities. MCH1 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal serine338/threonine342 (pS338/pT342-MCH1) and threonine348/serine350 (pT348/pS350-MCH1). This nomenclature refers to the human MCH1 receptor but is identical in mice and rats. For more information on MCH1 receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Audinot V, Boutin JA, Lakaye B, Nahon JL, Saito Y. Melanin-concentrating hormone receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F37/2023.1.

The melanin-concentrating hormone receptor 1 (MCH1) is the receptor for a 19 amino-acids cyclic peptide. The highest expression of MCH1 is found in the brain: frontal cortex, amygdala and nucleus... read more »
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Immuno-Grade Melanin-Concentrating Hormone Receptor 1 (MCH1) Antibodies

The melanin-concentrating hormone receptor 1 (MCH1) is the receptor for a 19 amino-acids cyclic peptide. The highest expression of MCH1 is found in the brain: frontal cortex, amygdala and nucleus accumbens, but also in the arcuate nucleus and in the ventral medial hypothalamus. MCH1 seems to play a role in appetite regulation and obesity. Knock out mice for MCH1 are leaner, even on high fat diet. Several antagonists at MCH1 showed antidepressant and anxiolytic activities. MCH1 receptor desensitization, β-arrestin recruitment and internalization are regulated by phosphorylation of carboxyl-terminal serine338/threonine342 (pS338/pT342-MCH1) and threonine348/serine350 (pT348/pS350-MCH1). This nomenclature refers to the human MCH1 receptor but is identical in mice and rats. For more information on MCH1 receptor pharmacology please refer to the IUPHAR database. For further reading refer to:

Audinot V, Boutin JA, Lakaye B, Nahon JL, Saito Y. Melanin-concentrating hormone receptors in GtoPdb v.2023.1. IUPHAR/BPS Guide to Pharmacology CITE. 2023; 2023(1). Available from: https://doi.org/10.2218/gtopdb/F37/2023.1.

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